The latest Resident Evil film opened in the United States and Canada on the weekend of September 18–20, 2026, generating $60 million in ticket sales. The earnings placed the movie at the top of the North American box office for the weekend and marked the highest opening weekend ever recorded for the franchise.

The picture was directed by Zach Cregger and released by Sony Pictures. Cregger’s involvement follows his previous work in the series, and Sony Pictures handled distribution across North America.

The film was shown in 3,684 theaters across the two‑nation market. The $60 million total reflects the combined revenue from all venues during the three‑day opening period.

The strong debut contributed a noticeable increase to the overall North American box office performance for the weekend, providing a boost to industry totals as the market opened its weekend with the franchise’s top‑grossing start.

Resident Evil, a long‑running series of horror‑action movies, added this latest entry to its catalog with the record‑setting opening. The $60 million figure surpasses all previous first‑weekend earnings for any Resident Evil title, establishing a new benchmark for the brand’s commercial performance in the region.